Search on: V-ERBB PROTEINS 
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Descriptor English:   Oncogene Proteins v-erbB 
Descriptor Spanish:   Proteínas Oncogénicas v-erbB 
Descriptor Portuguese:   Proteínas Oncogênicas v-erbB 
Synonyms English:   erbB Oncogene Proteins
v-erbB Proteins  
Tree Number:   D12.776.624.664.520.750.883
D12.776.964.700.750.883
D12.776.964.775.750.883
Definition English:   Transforming proteins encoded by erbB oncogenes from the avian erythroblastosis virus. The protein is a truncated form of the EGF receptor (RECEPTOR, EPIDERMAL GROWTH FACTOR) whose kinase domain is constitutively activated by deletion of the ligand-binding domain. 
Indexing Annotation English:   IM; coord with specific virus (IM); /drug eff /ultrastruct permitted; DF: note short X ref
History Note English:   95; was ONCOGENE PROTEINS ERBB (NM) 1987-94 
Allowable Qualifiers English:  
administration & dosage adverse effects
agonists antagonists & inhibitors
analysis biosynthesis
blood cerebrospinal fluid
chemistry classification
chemical synthesis contraindications
drug effects deficiency
diagnostic use economics
genetics history
immunology isolation & purification
metabolism pharmacology
physiology pharmacokinetics
poisoning radiation effects
supply & distribution secretion
standards toxicity
therapeutic use ultrastructure
urine  
Record Number:   32105 
Unique Identifier:   D018739 

Occurrence in VHL:
 

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